Description
Product Characteristics:
Lysosomal-associated transmembrane protein 4A (LAPTM4A), also known as Golgi 4-transmembrane spanning transporter MTP, is a 233 amino acid protein belonging to the LAPTM5/LAPTM5 transporter family. LAPTM4A is subcellularly localized to the intracytoplasmic membrane and has the potential to reside in intracellular membrane-bound compartments. LAPTM4A is thought to function as a transporter of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of intracellular compartments. LAPTM4A is predicted to have four transmembrane domains, with the C-terminal domain being required for retention of the protein within intracellular membranes. May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment
Subcellular location: Endoplasmic reticulum
Synonyms: Golgi 4 transmembrane spanning transporter MTP, Golgi 4-transmembrane-spanning transporter MTP, HUMORF13, KIAA0108, LAP4A_HUMAN, LAPTM4, LAPTM4A, Lysosomal associated protein transmembrane 4 alpha, Lysosomal associated transmembrane protein 4A, Lysosomal protein transmembrane 4 alpha, Lysosomal-associated transmembrane protein 4A, MBNT, Membrane nucleoside transporter, MTRP.
Target Information: This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined\, however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. [provided by RefSeq, Jul 2008]